Patients with progressive Keratoconus when treated with cornea cross linking with riboflavin may face some side effects. The most common ocular adverse reactions were corneal opacity or haze, corneal folds or striae, superficial keratitis or punctate epitheliopathy. As we create the epithelial defect by removing the epithelium layer there can be pain and delayed healing. Blurred vision can occur from this or from corneal haze.
That is why FDA monitoring and approval is important. That way a patient can know the true incidence before deciding on the procedure. Risks benefits allow proper sight saving decisions to be made.
The management of the complications arising from C3R procedure requires a cornea trained Keratoconus expert. A thorough understanding of the anatomy of the cornea and its physiology is required. The procedure involves three steps – a surgical, a chemical and a radiation step. Each portion can cause problems. The different side effects can interact further confusing the picture. A keratoconus surgeon has to be like Sherlock Holmes deciphering the clues to come up with a proper effective treatment regimen for complications.